I have recently been questioned about inheritance of osteosarcoma in Irish Setters. Fortunately this is not something I have personal experience of. I do know some medium to large breeds are more prone to this form of cancer. The view generally seems to be that cancer is on the increase, but I do not know if there is scientific evidence to support this.
I was surprised by the opininon that osteosarcoma was linked with being female. This does not make sense to me - but I'm no expert.
I'd be pleased to hear your views.